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Cat No. | Product Name | Synonyms | Targets |
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T28009 | ME-3221 | ME3221 | |
Apomine is an inhibitor of HMG-CoA-reductase. It promotes apoptosis of myeloma cells in vitro and is associated with a modulation of myeloma in vivo. Apomine enhances the antitumor effects of lovastatin on myeloma cells ... | |||
T72025 | PCSK9-IN-10 | Serine/threonin kinase | |
PCSK9-IN-10, a potent and orally active inhibitor of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9), exhibits a half-maximal inhibitory concentration (IC50) of 6.4 µM. By enhancing the expression of Low-Density Li... | |||
T26644 | Apomine | SK&F-99085,APB-231-A2,APB-231-A-2,SR-9223i,SK&F-99085,SR-45023A | HMG-CoA Reductase |
Apomine (SR-9223i), an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and has been implicated in the regulation of myeloma in vivo. Apomine accelerates the degradation of 3-hydroxy-3-methylg... | |||
T15561 | Imanixil | HOE-402(free base) | Others |
Imanixil is an inducer of the LDL receptor (LDLR) and it is also a potent cholesterol-lowering compound. It also inhibits very low density-lipoprotein (VLDL) production and consequently decreases atherosclerosis developm... | |||
T74577 | Milpocitide | ||
Milpocitide, a (293-333)-peptide fragment of the human low-density lipoprotein receptor (LDLR), specifically corresponds to the EGF-like domain 1 [1]. | |||
T36180 | Azelaoyl PAF | ||
Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes via the nuclear receptor PPARγ. One of these substances was recently isolated and pur... | |||
T36171 | KDdiA-PC | ||
Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as ... | |||
T77144 | Recaticimab | ||
Recaticimab (SHR-1209) is a humanized monoclonal antibody targeting PCSK9 to enhance the degradation of this enzyme. By binding to PCSK9, Recaticimab elevates low-density lipoprotein (LDL) receptor presence on hepatocyte... | |||
T78034 | ANG1005 | ||
ANG1005 is a brain-penetrating peptide-agent conjugate comprising a taxane derivative that features three paclitaxel molecules covalently bonded to Angiopep-2. This design facilitates crossing of the blood-brain and bloo... | |||
T62598 | Pitavastatin sodium | ||
Pitavastatin (NK-104) sodium is a potent inhibitor of hydroxymethylglutaryl-CoA (HMG-CoA) reductase and a potent inducer of the hepatocyte low-density lipoprotein cholesterol (LDL-C) receptor. pitavastatin sodium inhibit... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5S0246 | Pseudoprotodioscin | Others , Fatty Acid Synthase | |
1. Pseudoprotodioscin has moderate cytotoxicity. | |||
T77289 | 5-O-Methylembelin | ||
5-O-Methylembelin is a natural isocoumarin that inhibits PCSK9 , low-density lipoprotein receptor (IDOL) , and sterol regulatory element binding protein 2 (SREBP2) mRNA expression [1] . | |||
T36563 | (E)-Guggulsterone | ||
Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulat... |
Cat No. | Product Name | Species | Expression System |
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TMPY-00989 | LDLR Protein, Human, Recombinant (His) | Human | HEK293 |
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i... | |||
TMPY-01085 | VLDLR Protein, Human, Recombinant (His) | Human | HEK293 |
The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and A... | |||
TMPY-01014 | LDLR Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i... | |||
TMPY-05348 | LDLR Protein, Mouse, Recombinant (His), Biotinylated | Mouse | HEK293 |
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i... | |||
TMPJ-00394 | LDLR Protein, Human, Recombinant (Avi & His), Biotinylated | Human | Human Cells |
Low-density lipoprotein receptor 9 (LDL receptor) is a single-pass type I membrane protein which belongs to the LDLR family. It contains 3 EGF-like domains, 7 LDL-receptor class A domains, and 6 LDL-receptor class B repe... | |||
TMPY-05323 | LDLR Protein, Human, Recombinant (mFc) | Human | HEK293 |
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i... | |||
TMPY-05499 | LDLR Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i... | |||
TMPY-05809 | LDLR Protein, Human, Recombinant (193D/A, His) | Human | HEK293 |
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i... | |||
TMPY-03351 | LOX-1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-liga... | |||
TMPY-00383 | LDLRAD3 Protein, Human, Recombinant (hFc) | Human | HEK293 |
LDLRAD3 Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 43.8 kDa. Accession number: Q86YD5-1 | |||
TMPY-03975 | LRP-11 Protein, Human, Recombinant (His) | Human | HEK293 |
LRP-11 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 45.3 kDa. Accession number: Q86VZ4-1 | |||
TMPY-04066 | LOX-1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-liga... | |||
TMPY-03371 | LOX-1 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-liga... | |||
TMPY-02748 | LRP-10 Protein, Human, Recombinant (His) | Human | HEK293 |
LRP10 (low-density lipoprotein Receptor Related Protein 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a low-density lipoprotein receptor family protein. A simi... | |||
TMPY-02653 | LRP-10 Protein, Human, Recombinant (hFc) | Human | HEK293 |
LRP10 (low-density lipoprotein Receptor Related Protein 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a low-density lipoprotein receptor family protein. A simi... | |||
TMPJ-01412 | LRP-12 Protein, Human, Recombinant (His) | Human | Human Cells |
Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 c... | |||
TMPY-02490 | LOX-1 Protein, Human, Recombinant (His) | Human | HEK293 |
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-liga... | |||
TMPY-01732 | LRPAP1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Receptor-associated protein (RAP) is a molecular chaperone for low-density lipoprotein receptor-related protein (LRP), which plays a key role in cholesterol metabolism. The lipoprotein receptor-related protein (LRP) is a... | |||
TMPY-01233 | LRPAP1 Protein, Human, Recombinant (His) | Human | HEK293 |
Receptor-associated protein (RAP) is a molecular chaperone for low-density lipoprotein receptor-related protein (LRP), which plays a key role in cholesterol metabolism. The lipoprotein receptor-related protein (LRP) is a... | |||
TMPY-05131 | PCSK9 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec... | |||
TMPY-00408 | PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His) | Human | HEK293 |
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec... | |||
TMPY-04966 | PCSK9 Protein, Human, Recombinant (D374Y, His) | Human | HEK293 |
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec... | |||
TMPY-01469 | Frizzled 5 Protein, Human, Recombinant (His) | Human | HEK293 |
Wnt signaling is involved in a variety of embryonic development processes of nonvertebrates and vertebrates, where it determines cell motility, cell polarity, differentiation, proliferation and apoptosis, as well as form... | |||
TMPY-01608 | Decorin Protein, Human, Recombinant (His) | Human | HEK293 |
Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core p... | |||
TMPY-05337 | CXCL16 Protein, Human, Recombinant (His) | Human | HEK293 |
C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 exists in transmemb... | |||
TMPH-02515 | APOC1 Protein, Mouse, Recombinant (His) | Mouse | in vitro E. coli expression system |
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the tria... | |||
TMPH-03199 | APOE Protein, Rabbit, Recombinant (His & Myc & SUMO) | Rabbit | E. coli |
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plas... | |||
TMPJ-00756 | Apolipoprotein E/APOE3 Protein, Human, Recombinant (His) | Human | Human Cells |
ApoE, a glycoprotein, is a structural component of very low density lipoprotein (vLDL) synthesized by the liver and intestinally synthesized chylomicrons . ApoE is also a constituent of a subclass of high density of lipo... | |||
TMPK-01297 | LDLR Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
The low density lipoprotein receptor (LDLR) is the founding member of the LDL R family of widely expressed cell surface scavenger receptors. It is a cell-surface receptor that recognizes the apoprotein B100 which is embe... | |||
TMPK-00402 | LDLR Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
The low density lipoprotein receptor (LDLR) is the founding member of the LDL R family of widely expressed cell surface scavenger receptors. It is a cell-surface receptor that recognizes the apoprotein B100 which is embe... | |||
TMPH-02421 | APOE Protein, Cynomolgus, Recombinant (His & Myc) | Cynomolgus | E. coli |
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plas... | |||
TMPY-06834 | LRP-6 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Lipoprotein receptor-related protein 6 (LRP6) binds to Wnt ligands to transduce signal by stabilization of beta-catenin, which has been involved in the regulation of embryonic development and metabolism. Low density lipo... | |||
TMPJ-00443 | PCSK9 Protein, Macaca nemestrina, Recombinant (His) | Macaca nemestrina | Human Cells |
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in ... | |||
TMPK-00739 | LRP-5 Protein, Human, Recombinant (hFc) | Human | HEK293 |
A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that ... | |||
TMPK-00740 | LRP-5 Protein, Human, Recombinant (mFc) | Human | HEK293 |
A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that ... | |||
TMPY-06698 | LRP-6 Protein, Human, Recombinant (His) | Human | HEK293 |
Lipoprotein receptor-related protein 6 (LRP6) binds to Wnt ligands to transduce signal by stabilization of beta-catenin, which has been involved in the regulation of embryonic development and metabolism. Low density lipo... | |||
TMPK-00290 | CD36 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
CD36, alternatively known as platelet membrane glycoprotein IV (GPIV), GPIIIb, thrombospondin receptor, collagen receptor, fatty acid translocase (FAT), and scavenger receptor class B, member 3 (SR-B3), is an integral me... | |||
TMPK-00292 | CD36 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
CD36, alternatively known as platelet membrane glycoprotein IV (GPIV), GPIIIb, thrombospondin receptor, collagen receptor, fatty acid translocase (FAT), and scavenger receptor class B, member 3 (SR-B3), is an integral me... | |||
TMPK-00744 | LRP-6 Protein, Human, Recombinant (mFc) | Human | HEK293 |
Dickkopf-related protein 1 (DKK-1), a ligand for the WNT coreceptors low-density lipoprotein receptor-related proteins 5 and 6 (LRP-5 and LRP-6) and an inhibitor of WNT/β-catenin signaling, effectively inhibits pericyte ... | |||
TMPJ-00369 | PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated | Human | Human Cells |
Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processi... | |||
TMPJ-00368 | PCSK9 Protein, Human, Recombinant (Avi), Biotinylated | Human | Human Cells |
Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processi... | |||
TMPK-01155 | MANSC1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
MANSC1 contains 1 MANSC domain. MANSC is a seven-cysteine-containing domain present in animal membrane and extracellular proteins. MANSC (motif at N terminus with seven cysteines) is a novel domain with a well-conserved ... | |||
TMPY-01245 | PCSK9 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec... | |||
TMPY-05114 | PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His), Biotinylated | Human | HEK293 |
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec... | |||
TMPY-05217 | PCSK9 Protein, Mouse, Recombinant (mFc) | Mouse | HEK293 |
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec... | |||
TMPY-05270 | PCSK9 Protein, Human, Recombinant (D374Y, mFc), Biotinylated | Human | HEK293 |
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec... | |||
TMPY-05199 | PCSK9 Protein, Human, Recombinant (D374Y, mFc) | Human | HEK293 |
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec... | |||
TMPY-05218 | PCSK9 Protein, Human, Recombinant (mFc) | Human | HEK293 |
Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec... | |||
TMPJ-01331 | Frizzled-8 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | Human Cells |
Frizzled-8 is one of at least ten seven-transmembrane (7TM) glycoproteins of the Frizzled family of Wnt receptors. Frizzled proteins are thought to be G-protein-coupled. Wnt engagement, with low density lipoprotein recep... | |||
TMPJ-01332 | Frizzled-8 Protein, Human, Recombinant (His) | Human | Human Cells |
Frizzled-8 is one of at least ten seven-transmembrane (7TM) glycoproteins of the Frizzled family of Wnt receptors. Frizzled proteins are thought to be G-protein-coupled. Wnt engagement, with low density lipoprotein recep... | |||
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